AZ Cancer Center Translational Research Shared Resource

Overview of Services

The Bioinformatics Shared Resource supports all stages of a project, ranging from experimental design to analysis and publication of these data and development of grant applications. The BISR staff work individually with researchers to select the data analysis approach that would help answer the research question, with the ultimate goal of creating testable hypotheses and making fundamental new discoveries in cancer research. The Bioinformatics Shared Resource can help with a variety of analyses, including: 1) analysis of transriptomic, proteomic and other high-throughput data types, 2) analysis of cancer molecular and clinical data from public databases including NIH-TCGA, CCLE, GDSC, NIH-LINCS, and GEO, and 3) data integration and hypothesis generation through network analysis and pathway enrichment.

 

The Behavioral Measurement and Interventions Shared Resource (BMISR) has more than 25 years of experience providing support to UACC members and other University and national researchers studying human lifestyle behaviors related to cancer prevention and control, including diet, physical activity, tobacco exposure, quality of life, sun-safety, sleep and symptom management.  BMISR is a unique "one stop" resource that provides investigators one access point to several research services ranging from study design consultation to intervention delivery to data analysis.

 

The Genomics Core provides genomics services based on microarray and sequencing technology. The Core serves the research community with priority given first to members of our funding centers, then to other federally funded investigators at the University of Arizona, and then all other research investigators. As part of our commitment to providing high quality genomics service, the Core has qualified as a member of the Ion Torrent Certified Service Provider Program.

 

The Biostatistics Shared Resource (BSR) ensures excellent and timely biostatistical support in the design, development and analysis for all members of the University of Arizona Cancer Center (UACC).  The BSR provides efficient statistical design, accurate and organized data, and appropriate data analyses and interpretation to enable UACC investigators to achieve their scientific goals.  This support is facilitated by a team approach and the long-term dedicated involvement of specific BSR personnel embedded within all four of the UACC scientific programs. The BSR brings together a group of 10 individuals with specific expertise in biostatistics, clinical trials, statistical computing, and statistical database applications.  BSR faculty and staff are collaboratively involved in the conception, design, implementation, analysis, and reporting of laboratory, translational, clinical and population-based research conducted in the UACC.  

 Services Provided:

  • Clinical protocol development: Sample size justification and development of an appropriate statistical analysis approach 
  • Statistical considerations for funding applications: Translation of scientific objectives into statistically testable hypotheses, sample size and power justifications, and development of statistical analysis plans
  • Statistical analysis, interpretation, and assistance with manuscript preparation
  • Statistical review of UACC protocols by service on the Scientific Review Committee
  • Monitoring study safety and data integrity through service on the Data and Safety Monitoring Board

Leadership

Megha Padi, Ph.D. BISR Director mpadi@email.arizona.edu

Lois J. Loescher, Ph.D. BMISR Co-Director loescher@email.arizona.edu

Cynthia Thomson, Ph.D. BMISR Co-Director thomson@email.arizona.edu

George Watts, Ph.D. Genomic Co-Director gwatts@azcc.arizona.edu

Denise J. Roe, DrPH Professor, Director BSR droe@email.arizona.edu

Location and hours of operation

Hours: Location:

BMISR:

Monday-Friday

8AM-5PM 

 

BSR:

Monday -Friday

8:30AM-5:30PM

Bioinformatics Shared Resource:

 UACC 1st Floor

 

Behavioral Measurement and Interventions Shared Resource:

 3950 S. Country Club Rd

 Suite 330

 Tucson, AZ. 85714

 

Genomics Shared Service, Room 3933

 The University of Arizona Cancer Center

 1515 N. Campbell Ave.

 Tucson AZ 85724

 

BSR:

1515 N. Campbell Avenue

Tucson, AZ 85724

Links and Resources

  1. Bioinformatics Shared Resource
  2. Behavioral Measurement and Interventions Shared Resource
  3. Behavioral Measurement and Interventions Shared Resource Instrument Repository
  4. The Genomics Core

Contacts

Name Role Phone Email Location
Megha Padi
Bioinformatics Shared Resource Director
 
520-626-8003
 
mpadi@email.arizona.edu
 

 
Angela Yung
BMISR Operations Manager
 
520-626-8316
 
ayung@email.arizona.edu
 

 
George Watts
Genomic Co-Director
 
520-626-4724
 
gwatts@azcc.arizona.edu
 
Room 3933
 
Denise J. Roe, DrPH
Professor, Director, BSR
 
520-626-2281
 
droe@email.arizona.edu
 
Room 1933 UACC
 
Angela Wakeham
Program Coord. Sr.
 
520-626-2077
 
awakeham@email.arizona.edu
 
Room 1930 UACC
 

 

 

 

 

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