Analytical and Biological Mass Spectrometry

Analytical & Biological Mass Spectrometry Facility Policies

At the Analytical & Biological Mass Spectrometry Facility (ABMS), we have state-of-the-art equipment and unparalleled expertise for the analysis of a variety of biological and small molecules. One of our specializations includes protein-analysis encompassing: protein identification, protein and peptide sequence confirmation, intact protein molecular weight determination, complex protein sample analysis, and protein/antibody-drug interactions. In addition to proteomics, the ABMS team has developed an in-house metabolomics library (currently containing >700 compounds) to support metabolomic and lipidomics analysis, enabling the interrogation of the underlying metabolomic and lipidomics profiles. Through this proteomics, metabolomics, and lipidomics analysis, a greater in-depth and multi-omics profiling is achieved.

We can also identify a range of post-translational modifications (PTMs), determining their presence or absence, as well as quantitating the PTMs.

Our services are designed to assist you to answer your quantitative/qualitative proteomics and small molecule questions as well. The services include workflows for label free, chemical labeling (iTRAQ/TMT) and metabolic labeling (SILAC).

For chemists who would like to synthesize a molecule, we monitor the reaction step-by-step, calculate the percentage of product, test for its purity, and characterize the molecule with high resolution and high mass accuracy (typically better than 500 ppb [0.5 ppm] mass accuracy).

Whether you are interested in molecular weight and chemical composition determinations, structure elucidations and compound identification analysis or confirmation and accurate mass measurements of synthetic products, measurement of polymers, nucleic acids (DNA/RNA), peptides, proteins, natural products, and assistance with determination of unknowns. Or characterization of biological proteins, we look forward to supporting your research needs.

The Core is located in room 124J in the BIO5 Keating Bioresearch Building on the North Campus.

Email us with inquiries today at MassSpec@email.arizona.edu.

Personnel

Krishna Parsawar, MS, PhD
Manager
Email: krishnaparsawar@arizona.edu
Phone: (520) 626-4161

Yelena Feinstein, MS
Research Specialist
Email: feinstei@arizona.edu
Phone: (520) 626-4161

Kristen Kallen-Keck, BS
Analytical Research Coordinator
Email: keck@arizona.edu 
Phone: (520) 626-4161

Lawrence Walker, PhD                       
Assistant Staff Scientist
Email: larrywalker@arizona.edu    

Phone: (520) 626-4161

Ning Zhang,  PhD
Assistant Staff Scientist                        
Email: nzhang@arizona.edu             

Phone: (520) 626-4161

Hours

Locations

Monday - Friday

9:00 AM – 5:00 PM

24/7 Access for Trained Users

Keating Bioresearch Building, Room 124J

1657 E Helen Street

Tucson, AZ 85721

 (520) 626-4161

Samples may be dropped off at the UAGC freezer in the entryway to Room 106