UA Cancer Center - Biostatistics and Bioinformatics Shared Resource (BBSR)

Overview of Services

The Bioinformatics Team supports all stages of a project, ranging from experimental design to analysis and publication of these data and development of grant applications. The bioinformatics staff work individually with researchers to select the data analysis approach that would help answer the research question, with the ultimate goal of creating testable hypotheses and making fundamental new discoveries in cancer research. We can help with a variety of analyses, including: 1) analysis of transcriptomic, proteomic, metabolomic and other high-throughput data types, 2) analysis of cancer molecular and clinical data from public databases including NIH-TCGA, CCLE, GDSC, NIH-LINCS, and GEO, and 3) data integration and hypothesis generation through network analysis and pathway enrichment.

The Biostatistics Team ensures excellent and timely biostatistical support in the design, development and analysis for all members of the University of Arizona Cancer Center (UACC).  The biostatistics staff provide efficient statistical design, accurate and organized data, and appropriate data analyses and interpretation to enable UACC investigators to achieve their scientific goals.  This support is facilitated by a team approach and the long-term dedicated involvement of specific BBSR personnel embedded within all of the UACC scientific programs. The biostatistics team brings together a group of 8 individuals with specific expertise in biostatistics, clinical trials, statistical computing, and statistical database applications. Faculty and staff are collaboratively involved in the conception, design, implementation, analysis, and reporting of laboratory, translational, clinical and population-based research conducted in the UACC.  

 Services Provided:

• Clinical protocol development: Sample size justification and development of an appropriate statistical analysis approach 
• Statistical considerations for funding applications: Translation of scientific objectives into statistically testable hypotheses, sample size and power justifications, and development of statistical analysis plans
• Statistical analysis, interpretation, and assistance with manuscript preparation
• Statistical review of UACC protocols by service on the Scientific Review Committee
• Monitoring study safety and data integrity through service on the Data and Safety Monitoring Board

Leadership

Denise J. Roe, DrPH Professor, BBSR Co-Director droe@email.arizona.edu

Location and hours of operation

Bioinformatics Shared Resource

Contacts