CBC Molecular Structures Core

Overview of Services

The Molecular Structures Core (MSC) enables researchers to determine the structures and dynamics, or motions, of large biomolecules such as proteins and DNA to understand how they interact with each other and with small molecules such as drugs.  In addition to state-of-the-art equipment used to examine large molecules, experienced staff to help design and conduct experiments, as well as analyze data, provide training, and operate equipment is available.

The Bruker 800 and 600 MHz Avance NEO NMR spectrometers are optimized for biomolecular applications. Both are equipped with TCI cryoprobes for unparalleled signal-to-noise, allowing acquisition of protein spectra at as low as 10 μM concentration. The systems are capable of direct detection of ¹H, ²H, ¹³C, ¹⁵N, and ¹⁹F, and all channels other than ²H have the sensitivity advantage of cryo-cooled electronics.

Leadership 

Muhammed Shafeek O.H., Ph.D. | Researcher Scientist III
mshafeek@arizona.edu

Phone: 520-621-9735

Vlad Kumirov, Ph.D. | Assistant Staff Scientist
kumirov@arizona.edu

Phone: 520-621-8243

Jennifer Rascon | Coordinator, Budget and Finance
jrascon1@arizona.edu.520-626-7722

Staff hours
Monday - Thursday                 
12:00pm - 5:00pm

24/7 access for Trained Users           

1041 E Lowell St

Rooms 201 & 526

Tucson, AZ 95721